Liver problems after Itraconazole in cats

96 reports to the FDA describe liver problems in cats given Itraconazole. That is 22% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

96Reports
93%Marked serious
28%Recovered
8.3%Died or euthanised
30 daysTypical onset
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How soon it started

Same day
4 5.0%
1–2 days
1 1.3%
3–7 days
3 3.8%
1–4 weeks
41 51%
Over a month
31 39%

How the animals did

Recovered
26 27%
Recovered with lasting effects
1 1.0%
Still unwell when reported
27 28%
Euthanised
8 8.3%
Not known
34 35%

Problems reported at the same time

37 39%
34 35%
Kidney problems
12 13%
Dehydration
12 13%
Hyperglycaemia
11 11%

Age of the animals

Under 1 year
3
1–3 years
24
4–7 years
32
8–11 years
21
12+ years
15

About this medicine

Type: medicine.

Questions owners ask

Can Itraconazole cause liver problems in cats?
96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 30 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Itraconazole in cats · Medicines most reported with liver problems