Liver problems after Methylprednisolone in cats

The FDA has received 131 reports of liver problems in cats after Methylprednisolone. That is 8.2% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

131Reports
60%Marked serious
4.6%Recovered
35%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
26 28%
1–2 days
22 23%
3–7 days
18 19%
1–4 weeks
12 13%
Over a month
16 17%

How the animals did

Recovered
6 4.6%
Still unwell when reported
45 34%
Died
23 18%
Euthanised
23 18%
Not known
34 26%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
17
4–7 years
33
8–11 years
42
12+ years
29

About this medicine

Type: medicine.

Questions owners ask

Can Methylprednisolone cause liver problems in cats?
131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Methylprednisolone in cats · Medicines most reported with liver problems