Liver problems after Isoflurane in cats

The FDA has received 72 reports of liver problems in cats after Isoflurane. That is 3.5% of all reports for this medicine, compared with 2.8% across reports for all cat medicines.

72Reports
75%Marked serious
17%Recovered
42%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
34 52%
1–2 days
18 27%
3–7 days
7 11%
1–4 weeks
5 7.6%
Over a month
2 3.0%

How the animals did

Recovered
11 15%
Recovered with lasting effects
1 1.4%
Still unwell when reported
28 39%
Died
19 26%
Euthanised
11 15%
Not known
2 2.8%

Problems reported at the same time

Age of the animals

Under 1 year
14
1–3 years
7
4–7 years
13
8–11 years
26
12+ years
12

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause liver problems in cats?
72 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Isoflurane in cats · Medicines most reported with liver problems