Foaming at the mouth after Fluralaner (Bravecto) in cats

500 reports to the FDA describe foaming at the mouth in cats given Fluralaner. That is 4.7% of all reports for this medicine, compared with 1.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

500Reports
44%Marked serious
53%Recovered
1.6%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
411 93%
1–2 days
10 2.3%
3–7 days
4 0.9%
1–4 weeks
4 0.9%
Over a month
11 2.5%

How the animals did

Recovered
263 53%
Still unwell when reported
202 40%
Died
5 1.0%
Euthanised
3 0.6%
Not known
27 5.4%

Problems reported at the same time

Age of the animals

Under 1 year
73
1–3 years
201
4–7 years
95
8–11 years
51
12+ years
41

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause foaming at the mouth in cats?
500 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Foaming at the mouth with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with foaming at the mouth