Fever after Amoxicillin + Clavulanate (Clavamox) in cats

The FDA has received 129 reports of fever in cats after Amoxicillin + Clavulanate. That is 5.4% of all reports for this medicine, compared with 3.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

129Reports
40%Marked serious
11%Recovered
16%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
13 17%
1–2 days
22 29%
3–7 days
14 19%
1–4 weeks
19 25%
Over a month
7 9.3%

How the animals did

Recovered
14 11%
Still unwell when reported
37 29%
Died
12 9.3%
Euthanised
9 7.0%
Not known
57 44%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
37
4–7 years
32
8–11 years
22
12+ years
12

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause fever in cats?
129 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

All reported side effects of Amoxicillin + Clavulanate in cats · Medicines most reported with fever