Didn't work as expected after Amoxicillin + Clavulanate (Clavamox) in cats

The FDA has received 410 reports of didn't work as expected in cats after Amoxicillin + Clavulanate. That is 17% of all reports for this medicine, compared with 8.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

410Reports
24%Marked serious
3.4%Recovered
14%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
40 21%
1–2 days
22 11%
3–7 days
43 22%
1–4 weeks
46 24%
Over a month
42 22%

How the animals did

Recovered
14 3.4%
Still unwell when reported
131 32%
Died
38 9.3%
Euthanised
18 4.4%
Not known
209 51%

Problems reported at the same time

Loss of appetite
70 17%
Death
54 13%
Lethargy
50 12%
Vomiting
49 12%
Diarrhea
33 8.0%
Weight loss
33 8.0%
Kidney problems
27 6.6%
Fever
23 5.6%

Age of the animals

Under 1 year
78
1–3 years
57
4–7 years
78
8–11 years
57
12+ years
92

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause didn't work as expected in cats?
410 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Amoxicillin + Clavulanate in cats · Medicines most reported with didn't work as expected