Kidney problems after Amoxicillin + Clavulanate (Clavamox) in cats

The FDA has received 171 reports of kidney problems in cats after Amoxicillin + Clavulanate. That is 7.2% of all reports for this medicine, compared with 4.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

171Reports
46%Marked serious
2.9%Recovered
43%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
19 22%
1–2 days
13 15%
3–7 days
20 23%
1–4 weeks
22 25%
Over a month
14 16%

How the animals did

Recovered
5 2.9%
Still unwell when reported
44 26%
Died
51 30%
Euthanised
23 13%
Not known
48 28%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
25
4–7 years
40
8–11 years
31
12+ years
54

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause kidney problems in cats?
171 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Amoxicillin + Clavulanate in cats · Medicines most reported with kidney problems