Liver problems after Amoxicillin + Clavulanate (Clavamox) in cats

152 reports to the FDA describe liver problems in cats given Amoxicillin + Clavulanate. That is 6.4% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

152Reports
42%Marked serious
5.3%Recovered
32%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
15 21%
1–2 days
11 15%
3–7 days
15 21%
1–4 weeks
18 25%
Over a month
13 18%

How the animals did

Recovered
8 5.3%
Still unwell when reported
36 24%
Died
29 19%
Euthanised
19 13%
Not known
60 39%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
25
4–7 years
45
8–11 years
28
12+ years
29

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause liver problems in cats?
152 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Amoxicillin + Clavulanate in cats · Medicines most reported with liver problems