Fever after Doxycycline in cats

35 reports to the FDA describe fever in cats given Doxycycline. That is 14% of all reports for this medicine, compared with 3.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

35Reports

69%Marked serious

29%Recovered

23%Died or euthanised

3 daysTypical onset

How soon it started

Same day

6 19%

1–2 days

8 26%

3–7 days

2 6.5%

1–4 weeks

11 35%

Over a month

4 13%

How the animals did

Recovered

10 29%

Still unwell when reported

13 37%

Died

2 5.7%

Euthanised

6 17%

Not known

4 11%

Problems reported at the same time

20 57%

20 57%

18 51%

8 23%

7 20%

Behaviour change

7 20%

Leucocytosis

6 17%

Decreased packed cell volume (pcv)

6 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause fever in cats?: 35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Cefovecin (Convenia) 715 reports · 8.2% of its reports
Fever after Amoxicillin + Clavulanate (Clavamox) 129 reports · 5.4% of its reports
Fever after Enrofloxacin (Baytril) 64 reports · 4.1% of its reports
Fever after Amoxicillin 30 reports · 5.8% of its reports

All reported side effects of Doxycycline in cats · Medicines most reported with fever