Colic after Pyrantel in horses

The FDA has received 27 reports of colic in horses after Pyrantel. That is 2.9% of all reports for this medicine, compared with 4.2% across reports for all horse medicines.

27Reports

37%Marked serious

56%Recovered

22%Died or euthanised

1 daysTypical onset

How soon it started

Same day

8 44%

1–2 days

3 17%

3–7 days

2 11%

1–4 weeks

2 11%

Over a month

3 17%

How the animals did

Recovered

15 56%

Still unwell when reported

1 3.7%

Died

2 7.4%

Euthanised

4 15%

Not known

5 19%

Problems reported at the same time

Death

5 19%

Lethargy

4 15%

Loss of appetite

3 11%

Overdose

2 7.4%

Didn't work as expected

2 7.4%

Appetite loss

2 7.4%

Loose stool

2 7.4%

Nasal discharge

2 7.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause colic in horses?: 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Pyrantel in horses · Medicines most reported with colic