Didn't work as expected after Pyrantel in horses

The FDA has received 263 reports of didn't work as expected in horses after Pyrantel. That is 28% of all reports for this medicine, compared with 23% across reports for all horse medicines.

263Reports

1.5%Marked serious

1.5%Recovered

5.3%Died or euthanised

70 daysTypical onset

How soon it started

Same day

1 5.9%

1–2 days

0 0.0%

3–7 days

0 0.0%

1–4 weeks

2 12%

Over a month

14 82%

How the animals did

Recovered

4 1.5%

Still unwell when reported

4 1.5%

Died

13 4.9%

Euthanised

1 0.4%

Not known

241 92%

Problems reported at the same time

Abdominal pain

29 11%

Didn't stop worms

21 8.0%

Death

13 4.9%

Digestive tract disorder

11 4.2%

Diarrhea

9 3.4%

Loss of condition

8 3.0%

Lethargy

7 2.7%

Loss of appetite

7 2.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause didn't work as expected in horses?: 263 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 70 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

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