Lethargy after Pyrantel in horses

54 reports to the FDA describe lethargy in horses given Pyrantel. That is 5.8% of all reports for this medicine, compared with 7.9% across reports for all horse medicines.

54Reports
7.4%Marked serious
13%Recovered
11%Died or euthanised
–Typical onset
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How the animals did

Recovered
7 13%
Still unwell when reported
1 1.9%
Died
6 11%
Not known
40 74%

Problems reported at the same time

6 11%
Loose stool
6 11%
Liver problems
4 7.4%

Age of the animals

Under 1 year
4
1–3 years
3
4–7 years
7
8–11 years
5
12+ years
19

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause lethargy in horses?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Pyrantel in horses · Medicines most reported with lethargy