Recumbency after Moxidectin (ProHeart 6) in horses
142 reports to the FDA describe recumbency in horses given Moxidectin. That is 10% of all reports for this medicine, compared with 3.7% across reports for all horse medicines, so it is reported unusually often with this medicine.
142Reports
2.1%Marked serious
0.0%Recovered
28%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this ingredient include ProHeart 6, ProHeart 12. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Moxidectin cause recumbency in horses?
- 142 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Recumbency with similar medicines
- Recumbency after Ivermectin + Praziquantel 77 reports · 2.9% of its reports
- Recumbency after Ivermectin (Heartgard) 66 reports · 9.6% of its reports
- Recumbency after Moxidectin + Praziquantel 21 reports · 5.6% of its reports
All reported side effects of Moxidectin in horses · Medicines most reported with recumbency