Colic after Clodronate Disodium in horses

59 reports to the FDA describe colic in horses given Clodronate Disodium. That is 19% of all reports for this medicine, compared with 4.2% across reports for all horse medicines, so it is reported unusually often with this medicine.

59Reports

90%Marked serious

71%Recovered

5.1%Died or euthanised

Same dayTypical onset

How soon it started

Same day

32 65%

1–2 days

8 16%

3–7 days

3 6.1%

1–4 weeks

3 6.1%

Over a month

3 6.1%

How the animals did

Recovered

42 71%

Euthanised

3 5.1%

Not known

14 24%

Problems reported at the same time

15 25%

14 24%

12 20%

12 20%

6 10%

6 10%

5 8.5%

Recumbency

5 8.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Clodronate Disodium cause colic in horses?: 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Colic with similar medicines

Colic after Omeprazole 49 reports · 2.5% of its reports
Colic after Pergolide 61 reports · 4.9% of its reports
Colic after Ceftiofur 89 reports · 7.3% of its reports
Colic after Detomidine 38 reports · 3.8% of its reports
Colic after Flunixin Meglumine 48 reports · 7.7% of its reports
Colic after Polysulfated Glycosaminoglycan 26 reports · 5.0% of its reports
Colic after Monensin Sodium 20 reports · 17% of its reports
Colic after Oxybendazole 54 reports · 49% of its reports

All reported side effects of Clodronate Disodium in horses · Medicines most reported with colic