Death after Ursodeoxycholic Acid in dogs

23 reports to the FDA describe death in dogs given Ursodeoxycholic Acid. That is 31% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

23Reports
100%Marked serious
0.0%Recovered
100%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
4 21%
1–2 days
2 11%
3–7 days
1 5.3%
1–4 weeks
4 21%
Over a month
8 42%

How the animals did

Died
5 22%
Euthanised
18 78%

Problems reported at the same time

Kidney problems
9 39%
Lethargy
8 35%
Elevated gamma-glutamyl transferase (ggt)
7 30%
Breathing problems
6 26%
Didn't work as expected
6 26%
Diarrhea
6 26%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
4
8–11 years
9
12+ years
10

About this medicine

Type: medicine.

Questions owners ask

Can Ursodeoxycholic Acid cause death in dogs?
23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Ursodeoxycholic Acid in dogs · Medicines most reported with death