Thrombocytosis after Trazodone in dogs

27 reports to the FDA describe thrombocytosis in dogs given Trazodone. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports

78%Marked serious

11%Recovered

37%Died or euthanised

88 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

1 5.3%

3–7 days

1 5.3%

1–4 weeks

3 16%

Over a month

14 74%

How the animals did

Recovered

2 7.4%

Recovered with lasting effects

1 3.7%

Still unwell when reported

8 30%

Died

1 3.7%

Euthanised

9 33%

Not known

6 22%

Problems reported at the same time

15 56%

10 37%

9 33%

8 30%

8 30%

Elevated cholesterol (total)

8 30%

Decreased haematocrit

8 30%

Breathing problems

7 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause thrombocytosis in dogs?: 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 88 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Thrombocytosis with similar medicines

Thrombocytosis after Gabapentin 101 reports · 1.1% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with thrombocytosis