Pain after Trazodone in dogs

The FDA has received 66 reports of pain in dogs after Trazodone. That is 2.6% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

66Reports

61%Marked serious

11%Recovered

23%Died or euthanised

16 daysTypical onset

How soon it started

Same day

14 28%

1–2 days

4 8.0%

3–7 days

5 10%

1–4 weeks

9 18%

Over a month

18 36%

How the animals did

Recovered

7 11%

Still unwell when reported

31 47%

Died

4 6.1%

Euthanised

11 17%

Not known

13 20%

Problems reported at the same time

30 45%

25 38%

20 30%

19 29%

18 27%

Injection site reaction

17 26%

Breathing problems

16 24%

Death

15 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause pain in dogs?: 66 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 16 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

Pain after Gabapentin 481 reports · 5.3% of its reports
Pain after Fluoxetine 28 reports · 1.1% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with pain