Monocytosis after Trazodone in dogs

56 reports to the FDA describe monocytosis in dogs given Trazodone. That is 2.2% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

56Reports

88%Marked serious

1.8%Recovered

41%Died or euthanised

29 daysTypical onset

How soon it started

Same day

3 6.5%

1–2 days

8 17%

3–7 days

6 13%

1–4 weeks

9 20%

Over a month

20 43%

How the animals did

Recovered with lasting effects

1 1.8%

Still unwell when reported

21 38%

Died

6 11%

Euthanised

17 30%

Not known

11 20%

Problems reported at the same time

41 73%

38 68%

33 59%

31 55%

27 48%

23 41%

22 39%

20 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause monocytosis in dogs?: 56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 29 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Monocytosis with similar medicines

Monocytosis after Gabapentin 164 reports · 1.8% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with monocytosis