Inappropriate urination after Trazodone in dogs

50 reports to the FDA describe inappropriate urination in dogs given Trazodone. That is 2.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

50Reports

58%Marked serious

14%Recovered

12%Died or euthanised

13 daysTypical onset

How soon it started

Same day

12 34%

1–2 days

2 5.7%

3–7 days

2 5.7%

1–4 weeks

6 17%

Over a month

13 37%

How the animals did

Recovered

7 14%

Still unwell when reported

25 50%

Died

2 4.0%

Euthanised

4 8.0%

Not known

12 24%

Problems reported at the same time

16 32%

9 18%

9 18%

8 16%

7 14%

7 14%

7 14%

Inappropriate defecation

6 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause inappropriate urination in dogs?: 50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate urination with similar medicines

Inappropriate urination after Gabapentin 216 reports · 2.4% of its reports
Inappropriate urination after Fluoxetine 27 reports · 1.0% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with inappropriate urination