Excessive thirst after Trazodone in dogs

The FDA has received 78 reports of excessive thirst in dogs after Trazodone. That is 3.1% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports

65%Marked serious

10%Recovered

24%Died or euthanised

28 daysTypical onset

How soon it started

Same day

9 16%

1–2 days

7 12%

3–7 days

4 7.0%

1–4 weeks

10 18%

Over a month

27 47%

How the animals did

Recovered

8 10%

Still unwell when reported

39 50%

Died

3 3.8%

Euthanised

16 21%

Not known

12 15%

Problems reported at the same time

52 67%

24 31%

24 31%

23 29%

19 24%

17 22%

17 22%

15 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause excessive thirst in dogs?: 78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 28 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

Excessive thirst after Gabapentin 479 reports · 5.3% of its reports
Excessive thirst after Selegiline (Anipryl) 191 reports · 4.6% of its reports
Excessive thirst after Fluoxetine 55 reports · 2.1% of its reports
Excessive thirst after Clomipramine (Clomicalm) 65 reports · 4.3% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with excessive thirst