Hypokalaemia after Trazodone in dogs

30 reports to the FDA describe hypokalaemia in dogs given Trazodone. That is 1.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports

90%Marked serious

3.3%Recovered

27%Died or euthanised

42 daysTypical onset

How soon it started

Same day

3 13%

1–2 days

4 17%

3–7 days

2 8.7%

1–4 weeks

1 4.3%

Over a month

13 57%

How the animals did

Recovered

1 3.3%

Still unwell when reported

11 37%

Died

1 3.3%

Euthanised

7 23%

Not known

10 33%

Problems reported at the same time

21 70%

19 63%

16 53%

13 43%

11 37%

10 33%

9 30%

8 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause hypokalaemia in dogs?: 30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 42 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypokalaemia with similar medicines

Hypokalaemia after Gabapentin 71 reports · 0.8% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with hypokalaemia