Urine abnormalities after Tramadol in dogs

55 reports to the FDA describe urine abnormalities in dogs given Tramadol. That is 1.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports

58%Marked serious

15%Recovered

29%Died or euthanised

11 daysTypical onset

How soon it started

Same day

7 17%

1–2 days

3 7.1%

3–7 days

5 12%

1–4 weeks

15 36%

Over a month

12 29%

How the animals did

Recovered

6 11%

Recovered with lasting effects

2 3.6%

Still unwell when reported

23 42%

Died

3 5.5%

Euthanised

13 24%

Not known

8 15%

Problems reported at the same time

35 64%

33 60%

29 53%

25 45%

23 42%

18 33%

16 29%

15 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause urine abnormalities in dogs?: 55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urine abnormalities with similar medicines

Urine abnormalities after Melarsomine (Immiticide) 32 reports · 0.1% of its reports
Urine abnormalities after Polysulfated Glycosaminoglycan 24 reports · 0.4% of its reports
Urine abnormalities after Diphenhydramine 33 reports · 0.7% of its reports
Urine abnormalities after Butorphanol 24 reports · 0.5% of its reports
Urine abnormalities after Cefpodoxime 38 reports · 0.9% of its reports
Urine abnormalities after Isoflurane 20 reports · 0.7% of its reports
Urine abnormalities after Cephalexin 22 reports · 0.8% of its reports
Urine abnormalities after Famotidine 52 reports · 2.0% of its reports
Urine abnormalities after Chondroitin + Glucosamine 35 reports · 1.3% of its reports
Urine abnormalities after Glucosamine 29 reports · 1.6% of its reports

All reported side effects of Tramadol in dogs · Medicines most reported with urine abnormalities