Neutropenia after Toceranib in dogs

The FDA has received 101 reports of neutropenia in dogs after Toceranib. That is 9.4% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

101Reports
22%Marked serious
4.0%Recovered
22%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
7 13%
1–2 days
0 0.0%
3–7 days
4 7.5%
1–4 weeks
28 53%
Over a month
14 26%

How the animals did

Recovered
4 4.0%
Still unwell when reported
41 41%
Died
18 18%
Euthanised
4 4.0%
Not known
34 34%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
24
8–11 years
47
12+ years
18

About this medicine

Type: medicine.

Questions owners ask

Can Toceranib cause neutropenia in dogs?
101 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

All reported side effects of Toceranib in dogs · Medicines most reported with neutropenia