Ocular discharge after Tobramycin in dogs

The FDA has received 26 reports of ocular discharge in dogs after Tobramycin. That is 22% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

85%Marked serious

12%Recovered

12%Died or euthanised

5 daysTypical onset

How soon it started

Same day

6 32%

1–2 days

3 16%

3–7 days

2 11%

1–4 weeks

6 32%

Over a month

2 11%

How the animals did

Recovered

3 12%

Still unwell when reported

6 23%

Euthanised

3 12%

Not known

14 54%

Problems reported at the same time

Corneal ulcer

16 62%

Keratoconjunctivitis sicca

11 42%

Corneal disorder

10 38%

Blepharospasm

9 35%

Skin redness

8 31%

Lethargy

7 27%

Eye disorder (for photophobia see 'neurological')

7 27%

Squinting

7 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tobramycin cause ocular discharge in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ocular discharge with similar medicines

Ocular discharge after Melarsomine (Immiticide) 23 reports · 0.1% of its reports
Ocular discharge after Diphenhydramine 52 reports · 1.1% of its reports
Ocular discharge after Cefpodoxime 32 reports · 0.8% of its reports
Ocular discharge after Florfenicol + Mometasone + Terbinafine 216 reports · 6.1% of its reports
Ocular discharge after Cephalexin 22 reports · 0.8% of its reports
Ocular discharge after Clotrimazole + Gentamicin + Mometasone 21 reports · 0.8% of its reports
Ocular discharge after Betamethasone + Florfenicol + Terbinafine 46 reports · 1.9% of its reports
Ocular discharge after Ketoconazole 66 reports · 2.9% of its reports
Ocular discharge after Etodolac 25 reports · 1.3% of its reports
Ocular discharge after Neomycin 23 reports · 5.2% of its reports

All reported side effects of Tobramycin in dogs · Medicines most reported with ocular discharge