Recumbency after Spinosad (Comfortis) in dogs

131 reports to the FDA describe recumbency in dogs given Spinosad. That is 0.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

131Reports
26%Marked serious
14%Recovered
31%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
13 45%
1–2 days
6 21%
3–7 days
2 6.9%
1–4 weeks
0 0.0%
Over a month
8 28%

How the animals did

Recovered
11 8.4%
Recovered with lasting effects
7 5.3%
Still unwell when reported
2 1.5%
Died
33 25%
Euthanised
7 5.3%
Not known
71 54%

Problems reported at the same time

Age of the animals

Under 1 year
28
1–3 years
28
4–7 years
18
8–11 years
31
12+ years
24

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause recumbency in dogs?
131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Recumbency with similar medicines

All reported side effects of Spinosad in dogs · Medicines most reported with recumbency