Elevated gamma-glutamyl transferase (ggt) after Spinosad (Comfortis) in dogs
54 reports to the FDA describe elevated gamma-glutamyl transferase (ggt) in dogs given Spinosad. That is 0.1% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported less often than average with this medicine.
54Reports
33%Marked serious
17%Recovered
20%Died or euthanised
15 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Spinosad kills fleas; monthly chewable.
Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Spinosad cause elevated gamma-glutamyl transferase (ggt) in dogs?
- 54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 15 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Elevated gamma-glutamyl transferase (ggt) with similar medicines
- Elevated gamma-glutamyl transferase (ggt) after Lufenuron + Milbemycin Oxime (Sentinel) 41 reports · 0.2% of its reports
All reported side effects of Spinosad in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)