Eye or vision problems after Sarolaner (Simparica) in dogs

The FDA has received 106 reports of eye or vision problems in dogs after Sarolaner. That is 0.6% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

106Reports
86%Marked serious
13%Recovered
16%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
35 37%
1–2 days
17 18%
3–7 days
9 9.5%
1–4 weeks
18 19%
Over a month
16 17%

How the animals did

Recovered
14 13%
Still unwell when reported
56 53%
Died
8 7.5%
Euthanised
9 8.5%
Not known
19 18%

Problems reported at the same time

Age of the animals

Under 1 year
15
1–3 years
17
4–7 years
22
8–11 years
29
12+ years
18

About this medicine

Sarolaner kills fleas, ticks and some mites; monthly.

Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Sarolaner cause eye or vision problems in dogs?
106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eye or vision problems with similar medicines

All reported side effects of Sarolaner in dogs · Medicines most reported with eye or vision problems