Abnormal cytology after Sarolaner (Simparica) in dogs
The FDA has received 23 reports of abnormal cytology in dogs after Sarolaner. That is 0.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.
23Reports
57%Marked serious
8.7%Recovered
4.3%Died or euthanised
30 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Sarolaner kills fleas, ticks and some mites; monthly.
Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Sarolaner cause abnormal cytology in dogs?
- 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 30 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Abnormal cytology with similar medicines
- Abnormal cytology after Fluralaner (Bravecto) 154 reports · 0.2% of its reports
- Abnormal cytology after Afoxolaner (NexGard) 58 reports · 0.1% of its reports
- Abnormal cytology after Lotilaner (Credelio) 26 reports · 0.3% of its reports
All reported side effects of Sarolaner in dogs · Medicines most reported with abnormal cytology