Restlessness or agitation after Pyrantel in dogs

60 reports to the FDA describe restlessness or agitation in dogs given Pyrantel. That is 1.3% of all reports for this medicine, compared with 1.6% across reports for all dog medicines.

60Reports

25%Marked serious

25%Recovered

10%Died or euthanised

Same dayTypical onset

How soon it started

Same day

23 68%

1–2 days

4 12%

3–7 days

0 0.0%

1–4 weeks

4 12%

Over a month

3 8.8%

How the animals did

Recovered

14 23%

Recovered with lasting effects

1 1.7%

Still unwell when reported

10 17%

Died

5 8.3%

Euthanised

1 1.7%

Not known

29 48%

Problems reported at the same time

17 28%

14 23%

12 20%

10 17%

10 17%

9 15%

9 15%

8 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause restlessness or agitation in dogs?: 60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

Restlessness or agitation after Pyrantel + Sarolaner (Simparica Trio) 456 reports · 0.9% of its reports
Restlessness or agitation after Febantel + Praziquantel + Pyrantel (Drontal Plus) 443 reports · 6.6% of its reports
Restlessness or agitation after Fenbendazole 253 reports · 4.3% of its reports
Restlessness or agitation after Praziquantel + Pyrantel 76 reports · 2.1% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with restlessness or agitation