Neutrophilia after Pyrantel in dogs

The FDA has received 41 reports of neutrophilia in dogs after Pyrantel. That is 0.9% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

41Reports

63%Marked serious

7.3%Recovered

32%Died or euthanised

6 daysTypical onset

How soon it started

Same day

9 30%

1–2 days

5 17%

3–7 days

4 13%

1–4 weeks

7 23%

Over a month

5 17%

How the animals did

Recovered

3 7.3%

Still unwell when reported

14 34%

Died

6 15%

Euthanised

7 17%

Not known

11 27%

Problems reported at the same time

29 71%

26 63%

22 54%

20 49%

19 46%

19 46%

16 39%

14 34%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause neutrophilia in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

Neutrophilia after Pyrantel + Sarolaner (Simparica Trio) 146 reports · 0.3% of its reports
Neutrophilia after Febantel + Praziquantel + Pyrantel (Drontal Plus) 22 reports · 0.3% of its reports
Neutrophilia after Fenbendazole 51 reports · 0.9% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with neutrophilia