Lameness after Pyrantel in dogs

The FDA has received 47 reports of lameness in dogs after Pyrantel. That is 1.0% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

47Reports

49%Marked serious

8.5%Recovered

19%Died or euthanised

11 daysTypical onset

How soon it started

Same day

9 28%

1–2 days

3 9.4%

3–7 days

3 9.4%

1–4 weeks

8 25%

Over a month

9 28%

How the animals did

Recovered

4 8.5%

Still unwell when reported

16 34%

Died

5 11%

Euthanised

4 8.5%

Not known

18 38%

Problems reported at the same time

18 38%

16 34%

13 28%

11 23%

10 21%

9 19%

9 19%

8 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause lameness in dogs?: 47 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lameness with similar medicines

Lameness after Pyrantel + Sarolaner (Simparica Trio) 147 reports · 0.3% of its reports
Lameness after Febantel + Praziquantel + Pyrantel (Drontal Plus) 20 reports · 0.3% of its reports
Lameness after Fenbendazole 44 reports · 0.7% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with lameness