Excessive thirst after Pyrantel in dogs

The FDA has received 42 reports of excessive thirst in dogs after Pyrantel. That is 0.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

42Reports

36%Marked serious

14%Recovered

24%Died or euthanised

3 daysTypical onset

How soon it started

Same day

7 32%

1–2 days

4 18%

3–7 days

2 9.1%

1–4 weeks

6 27%

Over a month

3 14%

How the animals did

Recovered

5 12%

Recovered with lasting effects

1 2.4%

Still unwell when reported

9 21%

Died

8 19%

Euthanised

2 4.8%

Not known

17 40%

Problems reported at the same time

15 36%

15 36%

15 36%

13 31%

10 24%

10 24%

8 19%

6 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause excessive thirst in dogs?: 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

Excessive thirst after Pyrantel + Sarolaner (Simparica Trio) 332 reports · 0.6% of its reports
Excessive thirst after Febantel + Praziquantel + Pyrantel (Drontal Plus) 62 reports · 0.9% of its reports
Excessive thirst after Fenbendazole 65 reports · 1.1% of its reports
Excessive thirst after Praziquantel + Pyrantel 27 reports · 0.7% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with excessive thirst