Drug dose administration interval too short after Pyrantel in dogs

The FDA has received 37 reports of drug dose administration interval too short in dogs after Pyrantel. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

37Reports
30%Marked serious
19%Recovered
0.0%Died or euthanised
79 daysTypical onset
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How soon it started

Same day
1 8.3%
1–2 days
2 17%
3–7 days
1 8.3%
1–4 weeks
2 17%
Over a month
6 50%

How the animals did

Recovered
7 19%
Still unwell when reported
3 8.1%
Not known
27 73%

Problems reported at the same time

Overdose
14 38%
Didn't work as expected
10 27%
Loss of appetite
9 24%
Didn't stop worms
8 22%
Vomiting
5 14%
Lethargy
4 11%
Diarrhea
3 8.1%
Tremors
2 5.4%

Age of the animals

Under 1 year
22
1–3 years
9
4–7 years
2
8–11 years
4
12+ years
0

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause drug dose administration interval too short in dogs?
37 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 79 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drug dose administration interval too short with similar medicines

All reported side effects of Pyrantel in dogs · Medicines most reported with drug dose administration interval too short