Hypotension after Propofol in dogs

The FDA has received 106 reports of hypotension in dogs after Propofol. That is 3.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

106Reports
64%Marked serious
38%Recovered
31%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
45 69%
1–2 days
6 9.2%
3–7 days
4 6.2%
1–4 weeks
5 7.7%
Over a month
5 7.7%

How the animals did

Recovered
40 38%
Still unwell when reported
16 15%
Died
25 24%
Euthanised
8 7.5%
Not known
17 16%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
36
4–7 years
19
8–11 years
22
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause hypotension in dogs?
106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypotension with similar medicines

All reported side effects of Propofol in dogs · Medicines most reported with hypotension