Heart block after Propofol in dogs

38 reports to the FDA describe heart block in dogs given Propofol. That is 1.2% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

38Reports

76%Marked serious

74%Recovered

5.3%Died or euthanised

Same dayTypical onset

How soon it started

Same day

26 93%

1–2 days

1 3.6%

3–7 days

0 0.0%

1–4 weeks

0 0.0%

Over a month

1 3.6%

How the animals did

Recovered

28 74%

Still unwell when reported

2 5.3%

Died

2 5.3%

Not known

6 16%

Problems reported at the same time

Bradycardia

20 53%

Arrhythmia

5 13%

Abnormal ecg

3 7.9%

Didn't work as expected

3 7.9%

Allergic reaction

3 7.9%

Premature ventricular contractions

3 7.9%

Underdose

3 7.9%

Death

2 5.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause heart block in dogs?: 38 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Heart block with similar medicines

Heart block after Butorphanol 30 reports · 0.7% of its reports
Heart block after Isoflurane 30 reports · 1.1% of its reports

All reported side effects of Propofol in dogs · Medicines most reported with heart block