Premature ventricular contractions after Propofol in dogs

The FDA has received 26 reports of premature ventricular contractions in dogs after Propofol. That is 0.8% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

88%Marked serious

65%Recovered

23%Died or euthanised

Same dayTypical onset

How soon it started

Same day

21 84%

1–2 days

3 12%

3–7 days

0 0.0%

1–4 weeks

0 0.0%

Over a month

1 4.0%

How the animals did

Recovered

17 65%

Still unwell when reported

3 12%

Died

4 15%

Euthanised

2 7.7%

Problems reported at the same time

Bradycardia

13 50%

Tachycardia

6 23%

Death

6 23%

Heart block 3rd degree

5 19%

4 15%

3 12%

3 12%

3 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause premature ventricular contractions in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Premature ventricular contractions with similar medicines

Premature ventricular contractions after Butorphanol 28 reports · 0.6% of its reports
Premature ventricular contractions after Isoflurane 26 reports · 0.9% of its reports

All reported side effects of Propofol in dogs · Medicines most reported with premature ventricular contractions