Restlessness or agitation after Prednisone in dogs

237 reports to the FDA describe restlessness or agitation in dogs given Prednisone. That is 2.7% of all reports for this medicine, compared with 1.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

237Reports
62%Marked serious
31%Recovered
15%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
70 38%
1–2 days
21 12%
3–7 days
21 12%
1–4 weeks
26 14%
Over a month
44 24%

How the animals did

Recovered
70 30%
Recovered with lasting effects
4 1.7%
Still unwell when reported
68 29%
Died
11 4.6%
Euthanised
24 10%
Not known
60 25%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
55
4–7 years
61
8–11 years
70
12+ years
47

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause restlessness or agitation in dogs?
237 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Prednisone in dogs · Medicines most reported with restlessness or agitation