Proprioception deficit after Prednisone in dogs

The FDA has received 89 reports of proprioception deficit in dogs after Prednisone. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

89Reports

85%Marked serious

6.7%Recovered

27%Died or euthanised

13 daysTypical onset

How soon it started

Same day

13 18%

1–2 days

7 9.6%

3–7 days

10 14%

1–4 weeks

16 22%

Over a month

27 37%

How the animals did

Recovered

6 6.7%

Still unwell when reported

52 58%

Died

7 7.9%

Euthanised

17 19%

Not known

7 7.9%

Problems reported at the same time

37 42%

35 39%

29 33%

25 28%

23 26%

23 26%

20 22%

18 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause proprioception deficit in dogs?: 89 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proprioception deficit with similar medicines

Proprioception deficit after Dexamethasone 30 reports · 1.1% of its reports

All reported side effects of Prednisone in dogs · Medicines most reported with proprioception deficit