Eosinopenia after Prednisone in dogs

76 reports to the FDA describe eosinopenia in dogs given Prednisone. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

76Reports
84%Marked serious
6.6%Recovered
29%Died or euthanised
22 daysTypical onset
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How soon it started

Same day
8 14%
1–2 days
5 8.9%
3–7 days
6 11%
1–4 weeks
13 23%
Over a month
24 43%

How the animals did

Recovered
4 5.3%
Recovered with lasting effects
1 1.3%
Still unwell when reported
32 42%
Died
6 7.9%
Euthanised
16 21%
Not known
17 22%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
12
4–7 years
36
8–11 years
21
12+ years
7

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause eosinopenia in dogs?
76 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 22 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eosinopenia with similar medicines

All reported side effects of Prednisone in dogs · Medicines most reported with eosinopenia