Elevated globulins after Prednisone in dogs

80 reports to the FDA describe elevated globulins in dogs given Prednisone. That is 0.9% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

80Reports

74%Marked serious

2.5%Recovered

28%Died or euthanised

14 daysTypical onset

How soon it started

Same day

11 18%

1–2 days

5 8.3%

3–7 days

6 10%

1–4 weeks

13 22%

Over a month

25 42%

How the animals did

Recovered

1 1.3%

Recovered with lasting effects

1 1.3%

Still unwell when reported

36 45%

Died

9 11%

Euthanised

13 16%

Not known

20 25%

Problems reported at the same time

50 63%

48 60%

37 46%

34 43%

25 31%

24 30%

22 28%

21 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause elevated globulins in dogs?: 80 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated globulins with similar medicines

Elevated globulins after Dexamethasone 47 reports · 1.7% of its reports

All reported side effects of Prednisone in dogs · Medicines most reported with elevated globulins