Liver problems after Nitenpyram (Capstar) in dogs

87 reports to the FDA describe liver problems in dogs given Nitenpyram. That is 0.8% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported less often than average with this medicine.

87Reports

48%Marked serious

5.7%Recovered

29%Died or euthanised

8 daysTypical onset

How soon it started

Same day

8 21%

1–2 days

5 13%

3–7 days

6 16%

1–4 weeks

7 18%

Over a month

12 32%

How the animals did

Recovered

4 4.6%

Recovered with lasting effects

1 1.1%

Still unwell when reported

14 16%

Died

19 22%

Euthanised

6 6.9%

Not known

43 49%

Problems reported at the same time

40 46%

38 44%

32 37%

25 29%

18 21%

18 21%

18 21%

16 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Nitenpyram kills adult fleas quickly; a single-dose tablet.

Products with this ingredient include Capstar. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Nitenpyram cause liver problems in dogs?: 87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Spinosad (Comfortis) 955 reports · 1.7% of its reports
Liver problems after Lufenuron + Milbemycin Oxime (Sentinel) 414 reports · 1.6% of its reports
Liver problems after Imidacloprid + Moxidectin (Advantage Multi) 197 reports · 1.5% of its reports
Liver problems after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 132 reports · 1.3% of its reports
Liver problems after Fipronil + S-methoprene (Frontline Plus) 68 reports · 2.3% of its reports
Liver problems after Flumethrin + Imidacloprid (Seresto) 47 reports · 2.1% of its reports
Liver problems after Fipronil 53 reports · 3.8% of its reports
Liver problems after Lufenuron 53 reports · 5.2% of its reports
Liver problems after Imidacloprid + Permethrin + Pyriproxyfen 21 reports · 2.8% of its reports
Liver problems after Imidacloprid + Permethrin 24 reports · 5.1% of its reports

All reported side effects of Nitenpyram in dogs · Medicines most reported with liver problems