Dehydration after Mirtazapine (Mirataz) in dogs

21 reports to the FDA describe dehydration in dogs given Mirtazapine. That is 7.3% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

81%Marked serious

0.0%Recovered

48%Died or euthanised

29 daysTypical onset

How soon it started

Same day

1 5.9%

1–2 days

3 18%

3–7 days

2 12%

1–4 weeks

3 18%

Over a month

8 47%

How the animals did

Still unwell when reported

9 43%

Euthanised

10 48%

Not known

2 9.5%

Problems reported at the same time

19 90%

16 76%

16 76%

12 57%

11 52%

10 48%

10 48%

8 38%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Mirtazapine stimulates appetite (cats: ointment applied to the ear).

Products with this ingredient include Mirataz. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Mirtazapine cause dehydration in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 29 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Maropitant (Cerenia) 570 reports · 4.8% of its reports
Dehydration after Capromorelin (Entyce) 57 reports · 3.8% of its reports

All reported side effects of Mirtazapine in dogs · Medicines most reported with dehydration