Septicaemia after Midazolam in dogs

20 reports to the FDA describe septicaemia in dogs given Midazolam. That is 1.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports

100%Marked serious

10%Recovered

55%Died or euthanised

2 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

10 56%

3–7 days

2 11%

1–4 weeks

4 22%

Over a month

0 0.0%

How the animals did

Recovered

2 10%

Still unwell when reported

4 20%

Died

5 25%

Euthanised

6 30%

Not known

3 15%

Problems reported at the same time

11 55%

11 55%

11 55%

10 50%

10 50%

Intestinal disorder

10 50%

Intestinal perforation

9 45%

Vomiting

7 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause septicaemia in dogs?: 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Septicaemia with similar medicines

Septicaemia after Tramadol 26 reports · 0.7% of its reports
Septicaemia after Propofol 25 reports · 0.8% of its reports
Septicaemia after Isoflurane 22 reports · 0.8% of its reports
Septicaemia after Ampicillin 27 reports · 2.8% of its reports

All reported side effects of Midazolam in dogs · Medicines most reported with septicaemia