Vocalising after Metronidazole in dogs

The FDA has received 88 reports of vocalising in dogs after Metronidazole. That is 2.8% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

88Reports

70%Marked serious

22%Recovered

41%Died or euthanised

4 daysTypical onset

How soon it started

Same day

20 28%

1–2 days

14 19%

3–7 days

9 13%

1–4 weeks

14 19%

Over a month

15 21%

How the animals did

Recovered

18 20%

Recovered with lasting effects

1 1.1%

Still unwell when reported

28 32%

Died

19 22%

Euthanised

17 19%

Not known

5 5.7%

Problems reported at the same time

41 47%

35 40%

35 40%

34 39%

34 39%

24 27%

20 23%

18 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause vocalising in dogs?: 88 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

Vocalising after Amoxicillin + Clavulanate (Clavamox) 160 reports · 3.0% of its reports
Vocalising after Doxycycline 84 reports · 2.1% of its reports
Vocalising after Cefovecin (Convenia) 122 reports · 3.2% of its reports
Vocalising after Enrofloxacin (Baytril) 138 reports · 3.7% of its reports
Vocalising after Amoxicillin 42 reports · 3.1% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with vocalising