Pacing after Metronidazole in dogs

24 reports to the FDA describe pacing in dogs given Metronidazole. That is 0.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

71%Marked serious

13%Recovered

33%Died or euthanised

15 daysTypical onset

How soon it started

Same day

4 24%

1–2 days

4 24%

3–7 days

0 0.0%

1–4 weeks

2 12%

Over a month

7 41%

How the animals did

Recovered

3 13%

Still unwell when reported

7 29%

Died

1 4.2%

Euthanised

7 29%

Not known

6 25%

Problems reported at the same time

15 63%

14 58%

12 50%

11 46%

9 38%

9 38%

8 33%

Restlessness or agitation

7 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause pacing in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pacing with similar medicines

Pacing after Amoxicillin + Clavulanate (Clavamox) 28 reports · 0.5% of its reports
Pacing after Cefovecin (Convenia) 24 reports · 0.6% of its reports
Pacing after Enrofloxacin (Baytril) 29 reports · 0.8% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with pacing