Malaise after Metronidazole in dogs

43 reports to the FDA describe malaise in dogs given Metronidazole. That is 1.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports

65%Marked serious

14%Recovered

16%Died or euthanised

15 daysTypical onset

How soon it started

Same day

4 12%

1–2 days

5 15%

3–7 days

4 12%

1–4 weeks

9 26%

Over a month

12 35%

How the animals did

Recovered

5 12%

Recovered with lasting effects

1 2.3%

Still unwell when reported

23 53%

Died

4 9.3%

Euthanised

3 7.0%

Not known

7 16%

Problems reported at the same time

26 60%

24 56%

20 47%

18 42%

9 21%

9 21%

9 21%

7 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause malaise in dogs?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

Malaise after Amoxicillin + Clavulanate (Clavamox) 49 reports · 0.9% of its reports
Malaise after Doxycycline 35 reports · 0.9% of its reports
Malaise after Cefovecin (Convenia) 40 reports · 1.1% of its reports
Malaise after Enrofloxacin (Baytril) 36 reports · 1.0% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with malaise