Dry mucous membrane after Metronidazole in dogs

45 reports to the FDA describe dry mucous membrane in dogs given Metronidazole. That is 1.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

45Reports

87%Marked serious

16%Recovered

42%Died or euthanised

5 daysTypical onset

How soon it started

Same day

3 7.9%

1–2 days

12 32%

3–7 days

6 16%

1–4 weeks

5 13%

Over a month

12 32%

How the animals did

Recovered

6 13%

Recovered with lasting effects

1 2.2%

Still unwell when reported

12 27%

Died

9 20%

Euthanised

10 22%

Not known

7 16%

Problems reported at the same time

36 80%

30 67%

29 64%

27 60%

24 53%

24 53%

19 42%

16 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause dry mucous membrane in dogs?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dry mucous membrane with similar medicines

Dry mucous membrane after Amoxicillin + Clavulanate (Clavamox) 28 reports · 0.5% of its reports
Dry mucous membrane after Doxycycline 20 reports · 0.5% of its reports
Dry mucous membrane after Enrofloxacin (Baytril) 45 reports · 1.2% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with dry mucous membrane