Hypotension after Methadone in dogs

The FDA has received 24 reports of hypotension in dogs after Methadone. That is 10% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports
83%Marked serious
50%Recovered
25%Died or euthanised
Same dayTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
12 80%
1–2 days
0 0.0%
3–7 days
1 6.7%
1–4 weeks
1 6.7%
Over a month
1 6.7%

How the animals did

Recovered
11 46%
Recovered with lasting effects
1 4.2%
Still unwell when reported
6 25%
Died
5 21%
Euthanised
1 4.2%

Problems reported at the same time

Bradycardia
7 29%
Vocalising
6 25%
5 21%
Hypothermia
5 21%
Unresponsive
5 21%
Arrhythmia
4 17%

Age of the animals

Under 1 year
0
1–3 years
7
4–7 years
6
8–11 years
5
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Methadone cause hypotension in dogs?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypotension with similar medicines

All reported side effects of Methadone in dogs · Medicines most reported with hypotension