Pr-heartworm disease after Melarsomine (Immiticide) in dogs

The FDA has received 20 reports of pr-heartworm disease in dogs after Melarsomine. That is 0.1% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

20Reports
0.0%Marked serious
0.0%Recovered
95%Died or euthanised
–Typical onset
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How the animals did

Died
19 95%
Not known
1 5.0%

Problems reported at the same time

19 95%
Pr-lung(s), lesion(s)
7 35%
Pr-liver, lesion(s)
5 25%
4 20%

Age of the animals

Under 1 year
0
1–3 years
5
4–7 years
7
8–11 years
5
12+ years
3

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause pr-heartworm disease in dogs?
20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Melarsomine in dogs · Medicines most reported with pr-heartworm disease