Blood in vomit after Melarsomine (Immiticide) in dogs

The FDA has received 226 reports of blood in vomit in dogs after Melarsomine. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

226Reports

27%Marked serious

8.4%Recovered

16%Died or euthanised

4 daysTypical onset

How soon it started

Same day

24 29%

1–2 days

13 15%

3–7 days

17 20%

1–4 weeks

13 15%

Over a month

17 20%

How the animals did

Recovered

18 8.0%

Recovered with lasting effects

1 0.4%

Still unwell when reported

35 15%

Died

32 14%

Euthanised

5 2.2%

Not known

135 60%

Problems reported at the same time

75 33%

62 27%

57 25%

39 17%

38 17%

35 15%

22 9.7%

20 8.8%

Age of the animals

Under 1 year

1–3 years

108

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause blood in vomit in dogs?: 226 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in vomit with similar medicines

Blood in vomit after Polysulfated Glycosaminoglycan 47 reports · 0.9% of its reports
Blood in vomit after Diphenhydramine 56 reports · 1.2% of its reports
Blood in vomit after Butorphanol 58 reports · 1.3% of its reports
Blood in vomit after Cefpodoxime 35 reports · 0.9% of its reports
Blood in vomit after Tramadol 40 reports · 1.1% of its reports
Blood in vomit after Propofol 25 reports · 0.8% of its reports
Blood in vomit after Isoflurane 24 reports · 0.9% of its reports
Blood in vomit after Atipamezole 25 reports · 0.9% of its reports
Blood in vomit after Famotidine 64 reports · 2.4% of its reports
Blood in vomit after Chondroitin + Glucosamine 23 reports · 0.9% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with blood in vomit